L-10 Secondary messengers, cAMP, DAG,IP3 and effectors adenylyl cyclase and guanylyl cyclase


Summary

This video explores the significance of secondary messengers like cyclic AMP in the heart's contraction. It discusses how cyclic AMP can strengthen the force of contraction by affecting calcium ion levels. Additionally, the impact of drugs on muscle contraction through modulation of cyclic AMP and calcium ions is explained. The role of phospholipids and protein kinases in cell membrane composition is highlighted, showcasing their influence on muscle relaxation and contraction in different muscle types. The video also touches on how repeated activation of protein kinases can lead to cellular growth or death.


Introduction to Secondary Messenger

Exploration of secondary messenger mentioned with a brief explanation.

Effects of Cyclic AMP

Discussion on how cyclic AMP can enhance force of attraction and contraction in the heart.

Role of Drugs in Muscle Contraction

Explanation of how drugs can affect muscle contraction by altering calcium ions and cyclic AMP levels.

Phospholipids and Tyrosine Kinase

Insight into phospholipids, protein kinase, and their role in cell membrane composition.

Cellular Response and Smooth Muscle Relaxation

Explanation on how protein kinases affect muscle relaxation and contraction, impacting smooth and skeletal muscles.

Role of Protein Kinase in Cell Growth

Discussion on the repeated activation of protein kinases leading to cellular growth and death.

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